List of reactions that have genes assigned in E. coli

Click the EC number below for predictions.

Common Name
EC alcohol dehydrogenase
EC homoserine dehydrogenase
EC glycerol dehydrogenase
EC mannitol-1-phosphate 5-dehydrogenase
EC UDP-glucose 6-dehydrogenase
EC histidinol dehydrogenase
EC shikimate dehydrogenase
EC D-lactate dehydrogenase
EC 3-hydroxyacyl-CoA dehydrogenase
EC malate dehydrogenase
EC malate dehydrogenase (oxaloacetate-decarboxylating)
EC malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
EC isocitrate dehydrogenase (NADP+)
EC phosphogluconate dehydrogenase (decarboxylating)
EC glucose-6-phosphate dehydrogenase
EC fructuronate reductase
EC tagaturonate reductase
EC 2-hydroxy-3-oxopropionate reductase
EC gluconate 5-dehydrogenase
EC lactaldehyde reductase
EC glyoxylate reductase (NADP+)
EC 3-isopropylmalate dehydrogenase
EC ketol-acid reductoisomerase
EC glycerol-3-phosphate dehydrogenase [NAD(P)+]
EC phosphoglycerate dehydrogenase
EC L-threonine 3-dehydrogenase
EC 3-dehydro-L-gulonate 2-dehydrogenase
EC dTDP-4-dehydrorhamnose reductase
EC UDP-N-acetylmuramate dehydrogenase
EC 2-dehydropantoate 2-reductase
EC 5-amino-6-(5-phosphoribosylamino)uracil reductase
EC IMP dehydrogenase
EC gluconate 2-dehydrogenase
EC galactitol 1-phosphate 5-dehydrogenase
EC 4-hydroxythreonine-4-phosphate dehydrogenase
EC L-idonate 5-dehydrogenase
EC 1-deoxy-D-xylulose-5-phosphate reductoisomerase
EC GDP-L-fucose synthase
EC 2,5-didehydrogluconate reductase
EC quinate/shikimate dehydrogenase
EC S-(hydroxymethyl)glutathione dehydrogenase
EC L-lactate dehydrogenase (cytochrome)
EC (S)-2-hydroxy-acid oxidase
EC quinoprotein glucose dehydrogenase
EC glycerol-3-phosphate dehydrogenase
EC malate dehydrogenase (acceptor)
EC formate dehydrogenase
EC betaine-aldehyde dehydrogenase
EC acetaldehyde dehydrogenase (acetylating)
EC aspartate-semialdehyde dehydrogenase
EC glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)
EC succinate-semialdehyde dehydrogenase [NAD(P)+]
EC glycolaldehyde dehydrogenase
EC lactaldehyde dehydrogenase
EC N-acetyl-gamma-glutamyl-phosphate reductase
EC phenylacetaldehyde dehydrogenase
EC glutamate-5-semialdehyde dehydrogenase
EC glutamyl-tRNA reductase
EC pyruvate dehydrogenase (cytochrome)
EC pyruvate dehydrogenase (acetyl-transferring)
EC oxoglutarate dehydrogenase (succinyl-transferring)
EC prephenate dehydrogenase
EC dihydrodipicolinate reductase
EC 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
EC precorrin-2 dehydrogenase
EC dihydroorotate oxidase
EC coproporphyrinogen oxidase
EC protoporphyrinogen oxidase
EC succinate dehydrogenase
EC glutamate dehydrogenase (NADP+)
EC glutamate synthase (NADPH)
EC pyridoxamine-phosphate oxidase
EC amine oxidase (copper-containing)
EC L-aspartate oxidase
EC D-amino-acid dehydrogenase
EC pyrroline-5-carboxylate reductase
EC dihydrofolate reductase
EC methylenetetrahydrofolate dehydrogenase (NADP+)
EC 1-pyrroline-5-carboxylate dehydrogenase
EC methylenetetrahydrofolate reductase [NAD(P)H]
EC proline dehydrogenase
EC NADH dehydrogenase (ubiquinone)
EC NADH dehydrogenase
EC nitrite reductase [NAD(P)H]
EC GMP reductase
EC nitrate reductase
EC sulfite reductase (NADPH)
EC dihydrolipoyl dehydrogenase
EC glutathione-disulfide reductase
EC phosphoadenylyl-sulfate reductase (thioredoxin)
EC 3-carboxyethylcatechol 2,3-dioxygenase
EC taurine dioxygenase
EC superoxide dismutase
EC 4-hydroxy-3-methylbut-2-enyl diphosphate reductase
EC 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
EC [formate-C-acetyltransferase]-activating enzyme
EC methionine synthase
EC 5-methyltetrahydropteroyltriglutamate-homocysteine
EC thymidylate synthase
EC 3-demethylubiquinone-9 3-O-methyltransferase
EC uroporphyrin-III C-methyltransferase
EC trans-aconitate 2-methyltransferase
EC glycine hydroxymethyltransferase
EC phosphoribosylglycinamide formyltransferase
EC phosphoribosylaminoimidazolecarboxamide formyltransferase
EC aminomethyltransferase
EC 3-methyl-2-oxobutanoate hydroxymethyltransferase
EC aspartate carbamoyltransferase
EC ornithine carbamoyltransferase
EC transketolase
EC transaldolase
EC acetolactate synthase
EC 1-deoxy-D-xylulose-5-phosphate synthase
EC amino-acid N-acetyltransferase
EC phosphate acetyltransferase
EC acetyl-CoA C-acetyltransferase
EC glycerol-3-phosphate O-acyltransferase
EC acetyl-CoA C-acyltransferase
EC glycine C-acetyltransferase
EC serine O-acetyltransferase
EC [acyl-carrier-protein] S-malonyltransferase
EC acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase
EC 3-oxoacyl-[acyl-carrier-protein] synthase
EC homoserine O-succinyltransferase
EC 8-amino-7-oxononanoate synthase
EC 1-acylglycerol-3-phosphate O-acyltransferase
EC formate C-acetyltransferase
EC diamine N-acetyltransferase
EC dihydrolipoyllysine-residue succinyltransferase
EC fatty-acyl-CoA synthase
EC arginine N-succinyltransferase
EC 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
EC acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine
EC glucosamine-1-phosphate N-acetyltransferase
EC citrate (Si)-synthase
EC 2-methylcitrate synthase
EC malate synthase
EC 2-isopropylmalate synthase
EC phosphorylase
EC alpha,alpha-trehalose-phosphate synthase (UDP-forming)
EC starch synthase
EC 4-alpha-glucanotransferase
EC lipid-A-disaccharide synthase
EC undecaprenyldiphospho-muramoylpentapeptide
EC purine-nucleoside phosphorylase
EC uridine phosphorylase
EC thymidine phosphorylase
EC adenine phosphoribosyltransferase
EC hypoxanthine phosphoribosyltransferase
EC uracil phosphoribosyltransferase
EC orotate phosphoribosyltransferase
EC nicotinate phosphoribosyltransferase
EC amidophosphoribosyltransferase
EC ATP phosphoribosyltransferase
EC anthranilate phosphoribosyltransferase
EC nicotinate-nucleotide diphosphorylase (carboxylating)
EC nicotinate-nucleotide-dimethylbenzimidazole
EC xanthine phosphoribosyltransferase
EC thiamine-phosphate diphosphorylase
EC methionine adenosyltransferase
EC UDP-N-acetylglucosamine 1-carboxyvinyltransferase
EC riboflavin synthase
EC geranyltranstransferase
EC dihydropteroate synthase
EC spermidine synthase
EC cob(I)yrinic acid a,c-diamide adenosyltransferase
EC 3-phosphoshikimate 1-carboxyvinyltransferase
EC di-trans,poly-cis-decaprenylcistransferase
EC cysteine synthase
EC cystathionine gamma-synthase
EC 3-deoxy-7-phosphoheptulonate synthase
EC 3-deoxy-8-phosphooctulonate synthase
EC hydroxymethylbilane synthase
EC 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
EC aspartate transaminase
EC histidinol-phosphate transaminase
EC acetylornithine transaminase
EC ornithine-oxo-acid transaminase
EC glutamine-fructose-6-phosphate transaminase (isomerizing)
EC succinyldiaminopimelate transaminase
EC 4-aminobutyrate transaminase
EC (S)-3-amino-2-methylpropionate transaminase
EC branched-chain-amino-acid transaminase
EC phosphoserine transaminase
EC aromatic-amino-acid transaminase
EC adenosylmethionine-8-amino-7-oxononanoate transaminase
EC valine-pyruvate transaminase
EC glucokinase
EC rhamnulokinase
EC galactokinase
EC 6-phosphofructokinase
EC gluconokinase
EC ribokinase
EC ribulokinase
EC xylulokinase
EC thymidine kinase
EC adenylyl-sulfate kinase
EC riboflavin kinase
EC glycerone kinase
EC glycerol kinase
EC glycerate kinase
EC pantothenate kinase
EC pyridoxal kinase
EC homoserine kinase
EC pyruvate kinase
EC 2-dehydro-3-deoxygluconokinase
EC uridine kinase
EC hydroxymethylpyrimidine kinase
EC hydroxyethylthiazole kinase
EC L-fuculokinase
EC 1-phosphofructokinase
EC 2-dehydro-3-deoxygalactonokinase
EC N-acylmannosamine kinase
EC shikimate kinase
EC inosine kinase
EC tetraacyldisaccharide 4'-kinase
EC tagatose-6-phosphate kinase
EC 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase
EC adenosylcobinamide kinase
EC acetate kinase
EC carbamate kinase
EC phosphoglycerate kinase
EC aspartate kinase
EC acetylglutamate kinase
EC glutamate 5-kinase
EC propionate kinase
EC phosphoenolpyruvate-protein phosphotransferase
EC adenylate kinase
EC nucleoside-diphosphate kinase
EC phosphomethylpyrimidine kinase
EC guanylate kinase
EC dTMP kinase
EC cytidylate kinase
EC thiamine-phosphate kinase
EC ribose-phosphate diphosphokinase
EC 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
EC FMN adenylyltransferase
EC pantetheine-phosphate adenylyltransferase
EC sulfate adenylyltransferase
EC UTP-glucose-1-phosphate uridylyltransferase
EC UDP-glucose-hexose-1-phosphate uridylyltransferase
EC nicotinate-nucleotide adenylyltransferase
EC mannose-1-phosphate guanylyltransferase (GDP)
EC UDP-N-acetylglucosamine diphosphorylase
EC glucose-1-phosphate thymidylyltransferase
EC glucose-1-phosphate adenylyltransferase
EC 3-deoxy-manno-octulosonate cytidylyltransferase
EC phosphatidate cytidylyltransferase
EC (2,3-dihydroxybenzoyl)adenylate synthase
EC 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
EC adenosylcobinamide-phosphate guanylyltransferase
EC CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
EC holo-[acyl-carrier-protein] synthase
EC CDP-diacylglycerol-serine O-phosphatidyltransferase
EC phospho-N-acetylmuramoyl-pentapeptide-transferase
EC adenosylcobinamide-GDP ribazoletransferase
EC pyruvate, water dikinase
EC selenide, water dikinase
EC thiosulfate sulfurtransferase
EC biotin synthase
EC acetate CoA-transferase
EC citrate CoA-transferase
EC phospholipase A1
EC hydroxyacylglutathione hydrolase
EC phosphoserine phosphatase
EC glucose-1-phosphatase
EC fructose-bisphosphatase
EC trehalose-phosphatase
EC histidinol-phosphatase
EC phosphoglycolate phosphatase
EC inositol-phosphate phosphatase
EC alpha-ribazole phosphatase
EC glycerophosphodiester phosphodiesterase
EC dGTPase
EC alpha-glucosidase
EC beta-glucosidase
EC alpha-galactosidase
EC beta-galactosidase
EC alpha,alpha-trehalase
EC 6-phospho-beta-glucosidase
EC alpha,alpha-phosphotrehalase
EC AMP nucleosidase
EC adenosylhomocysteine nucleosidase
EC methylthioadenosine nucleosidase
EC isochorismatase
EC asparaginase
EC glutaminase
EC formyltetrahydrofolate deformylase
EC acetylornithine deacetylase
EC succinyl-diaminopimelate desuccinylase
EC nicotinamidase
EC N-acetylglucosamine-6-phosphate deacetylase
EC glutathionylspermidine amidase
EC dihydroorotase
EC allantoinase
EC agmatinase
EC ureidoglycolate hydrolase
EC cytosine deaminase
EC adenine deaminase
EC guanine deaminase
EC adenosine deaminase
EC cytidine deaminase
EC methenyltetrahydrofolate cyclohydrolase
EC IMP cyclohydrolase
EC dCTP deaminase
EC GTP cyclohydrolase I
EC phosphoribosyl-AMP cyclohydrolase
EC GTP cyclohydrolase II
EC diaminohydroxyphosphoribosylaminopyrimidine deaminase
EC glucosamine-6-phosphate deaminase
EC dUTP diphosphatase
EC CDP-diacylglycerol diphosphatase
EC phosphoribosyl-ATP diphosphatase
EC bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
EC UDP-sugar diphosphatase
EC aspartate 1-decarboxylase
EC glutamate decarboxylase
EC ornithine decarboxylase
EC lysine decarboxylase
EC arginine decarboxylase
EC diaminopimelate decarboxylase
EC phosphoribosylaminoimidazole carboxylase
EC orotidine-5'-phosphate decarboxylase
EC phosphoenolpyruvate carboxylase
EC uroporphyrinogen decarboxylase
EC methylmalonyl-CoA decarboxylase
EC tartronate-semialdehyde synthase
EC indole-3-glycerol-phosphate synthase
EC phosphoenolpyruvate carboxykinase (ATP)
EC adenosylmethionine decarboxylase
EC 3-dehydro-L-gulonate-6-phosphate decarboxylase
EC deoxyribose-phosphate aldolase
EC threonine aldolase
EC fructose-bisphosphate aldolase
EC 2-dehydro-3-deoxy-phosphogluconate aldolase
EC L-fuculose-phosphate aldolase
EC rhamnulose-1-phosphate aldolase
EC 2-dehydro-3-deoxyglucarate aldolase
EC 2-dehydro-3-deoxy-6-phosphogalactonate aldolase
EC dihydroneopterin aldolase
EC tagatose-bisphosphate aldolase
EC isocitrate lyase
EC N-acetylneuraminate lyase
EC citrate (pro-3S)-lyase
EC 4-hydroxy-2-oxoglutarate aldolase
EC anthranilate synthase
EC methylisocitrate lyase
EC citryl-CoA lyase
EC naphthoate synthase
EC aminodeoxychorismate lyase
EC tryptophanase
EC carbonate dehydratase
EC fumarate hydratase
EC aconitate hydratase
EC altronate dehydratase
EC mannonate dehydratase
EC dihydroxy-acid dehydratase
EC 3-dehydroquinate dehydratase
EC phosphopyruvate hydratase
EC phosphogluconate dehydratase
EC enoyl-CoA hydratase
EC imidazoleglycerol-phosphate dehydratase
EC tryptophan synthase
EC porphobilinogen synthase
EC L(+)-tartrate dehydratase
EC 3-isopropylmalate dehydratase
EC glucarate dehydratase
EC galactarate dehydratase
EC dTDP-glucose 4,6-dehydratase
EC GDP-mannose 4,6-dehydratase
EC prephenate dehydratase
EC dihydrodipicolinate synthase
EC uroporphyrinogen-III synthase
EC 2-methylcitrate dehydratase
EC 2-oxopent-4-enoate hydratase
EC cyanate hydratase
EC threonine synthase
EC methylglyoxal synthase
EC 3-dehydroquinate synthase
EC chorismate synthase
EC aspartate ammonia-lyase
EC ethanolamine ammonia-lyase
EC L-serine ammonia-lyase
EC D-serine ammonia-lyase
EC threonine ammonia-lyase
EC argininosuccinate lyase
EC adenylosuccinate lyase
EC lactoylglutathione lyase
EC cystathionine beta-lyase
EC S-ribosylhomocysteine lyase
EC adenylate cyclase
EC 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
EC ferrochelatase
EC sirohydrochlorin ferrochelatase
EC alanine racemase
EC glutamate racemase
EC diaminopimelate epimerase
EC 3-hydroxybutyryl-CoA epimerase
EC ribulose-phosphate 3-epimerase
EC UDP-glucose 4-epimerase
EC L-ribulose-5-phosphate 4-epimerase
EC N-acylglucosamine-6-phosphate 2-epimerase
EC dTDP-4-dehydrorhamnose 3,5-epimerase
EC UDP-N-acetylglucosamine 2-epimerase
EC ADP-glyceromanno-heptose 6-epimerase
EC L-ribulose-5-phosphate 3-epimerase
EC triose-phosphate isomerase
EC L-arabinose isomerase
EC xylose isomerase
EC ribose-5-phosphate isomerase
EC mannose-6-phosphate isomerase
EC glucose-6-phosphate isomerase
EC glucuronate isomerase
EC L-rhamnose isomerase
EC 1-(5-phosphoribosyl)-5-[(5-
EC hydroxypyruvate isomerase
EC phosphoribosylanthranilate isomerase
EC L-fucose isomerase
EC isopentenyl-diphosphate delta-isomerase
EC dodecenoyl-CoA isomerase
EC phosphoglycerate mutase
EC phosphoglucomutase
EC phosphopentomutase
EC phosphomannomutase
EC phosphoglucosamine mutase
EC glutamate-1-semialdehyde 2,1-aminomutase
EC isochorismate synthase
EC methylmalonyl-CoA mutase
EC chorismate mutase
EC UDP-galactopyranose mutase
EC acetate-CoA ligase
EC succinate-CoA ligase (ADP-forming)
EC propionate-CoA ligase
EC long-chain-fatty-acid-[acyl-carrier-protein] ligase
EC o-succinylbenzoate-CoA ligase
EC phenylacetate-CoA ligase
EC aspartate-ammonia ligase
EC glutamate-ammonia ligase
EC NAD+ synthase
EC glutathionylspermidine synthase
EC pantoate-beta-alanine ligase
EC glutamate-cysteine ligase
EC glutathione synthase
EC D-alanine-D-alanine ligase
EC phosphoribosylaminoimidazolesuccinocarboxamide synthase
EC UDP-N-acetylmuramate-L-alanine ligase
EC UDP-N-acetylmuramoyl-L-alanine-D-glutamate ligase
EC UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
EC dihydrofolate synthase
EC UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate
EC tetrahydrofolate synthase
EC phosphoribosylformylglycinamidine cyclo-ligase
EC dethiobiotin synthase
EC CTP synthase
EC adenylosuccinate synthase
EC argininosuccinate synthase
EC phosphoribosylamine-glycine ligase
EC biotin carboxylase
EC GMP synthase (glutamine-hydrolysing)
EC phosphoribosylformylglycinamidine synthase
EC asparagine synthase (glutamine-hydrolysing)
EC carbamoyl-phosphate synthase (glutamine-hydrolysing)
EC aminodeoxychorismate synthase
EC acetyl-CoA carboxylase
EC DNA ligase (NAD+)
Candidate genes for an orphan metabolic activity

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